منابع مشابه
Non-secretory multiple myeloma with diagnostic challenges.
Non-secretory multiple myeloma (NSMM) is a rare variant of the classic form of multiple myeloma (MM). In NSMM, no monoclonal gammopathy can be detected in serum or urine by conventional techniques, making the diagnosis more difficult. We describe a 71-year-old man who had been diagnosed and treated for granulocytic sarcoma one year prior to his recent problems of progressive low-back pain of tw...
متن کاملNon Secretory Multiple Myeloma With HCV Infection: A Rare Case Entity
Multiple Myeloma is a neoplasm of B cell lineage characterized by excessive proliferation of abnormal plasma cells. It is characterized by a clinical pentad of 1) anemia, 2) a monoclonal protein in the serum or the urine or both, 3) bone leisons and or bone pain, 4) hypercalcemia >11.5g/dl and 5) renal insufficiency. Non secretory multiple myeloma is a rare variant of the classic form of multi...
متن کاملNon-secretory myeloma: a rare variant of multiple myeloma.
The spectrum of plasma cell neoplasm represents indolent conditions like Monoclonal Gammopathy of Undetermined Significance (MGUS) to more aggressive multiple myeloma and plasma cell leukemia. Non-secretory myeloma comprises less than 01% of this spectrum where serum protein electrophoresis and quantitative immunoglobulins remain essentially normal. We are presenting a case report of this rare ...
متن کاملNon-secretory multiple myeloma: from biology to clinical management
Multiple myeloma (MM) is the second most common hematologic malignancy in the US. It is typically characterized by production of large amounts of defective immunoglobulin (Ig). Diagnosing MM and monitoring treatment response, including eventual relapse, are largely based on sequential measurements of Ig. However, a small subset of MM called non-secretory multiple myeloma (NSMM) produces no dete...
متن کاملMegaloblastic anaemia in non secretory multiple myeloma: a rare presentation.
A 31-year old army soldier presented with a four day history of fever and malaise. He was a teetotaller and a non-vegetarian. Physical examination was unremarkable There was no lymphadenopathy or organomegaly. Fever subsided spontaneously. Investigations showed pancytopaenia (WBC 2.2 × 103/μl , L:65%, N:19%, platelets 77×103/μl, haemoglobin 10.5 g/dl). MCV was 106.5 fl. Blood picture was typica...
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ژورنال
عنوان ژورنال: Ceylon Medical Journal
سال: 2011
ISSN: 2386-1274,0009-0875
DOI: 10.4038/cmj.v48i2.3379